Vascular Endothelial Growth Factor

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Nowadays, one of the most widespread diseases is cancer. Creation of new antitumor medications has been so far a significant trend in the pharmacological industry. That’s why we created this stunning vascular endothelial growth factor animation and its receptors that are taking part in the vascularization of a malignant process and are the primary targets of some anticancer drugs.

What is the Vascular Endothelial Growth Factor?

Every day, our body forms new cells and tissues. These tissues need an adequate blood supply, from numerous blood vessels. The process of angiogenesis is stimulated by the vascular endothelial growth factor (VEGF) in the human body. It is essential during embryonic development as well as during formation of collateral blood flow in case of a blocked artery.VEGF (a cystine-knot growth factor) is an endothelial cell-specific angiogenic and vasculogenic mitogen as it binds only to receptors localized on vascular endothelial cells. VEGF is also called the (vascular permeability factor). This protein is transported in blood serum. VEGF is produced by various cell types including tumor cells, macrophages, platelets, keratinocytes and renal mesangial cells. It controls the oxygen supply and acts when hypoxic conditions occur. For example, serum contains more VEGF in pathologic conditions, such as diabetes mellitus and bronchial asthma. During the growth of the tumor, as during the growth of normal tissue, vascular endothelial growth factor plays one of the key roles. Rapid cell proliferation in a tumor progression leads to the formation of a vast number of new vessels, which is regulated by VEGF.

VEGF Receptors

The receptors are specific protein receptors that bind to VEGF. They can be found on the cell membrane or in the matrix. Because of their role in neoangiogenesis, they are the primary target for some medications used in cancer treatment.


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Nanobot Medical Animation Studio develops highly innovative digital graphics to depict actual and conceptual technologies by a synergistic fusion of art and science since 2007. Nanobot provides visually engaging digital solutions like scientific VR/AR/MR, 3D medical animations, illustrations for innovative marketing and training | education strategies to the pharmaceutical and biotech industry.We are devoted entirely to medical and scientific imaging. Our creative production team and experienced medical experts help us produce visually and scientifically accurate media material to make any project a huge success.We are a professional medical animation and interactive design company whose team has a long history of experience in the creation of latter-day colorful photo-realistic animated or static images.
Our client ranges from the Medical Device, Pharmaceutical and Biotechnology Industry, as well as Educational Institutes, Medical Marketing Companies, and Healthcare Agencies Globally.



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